Searchable abstracts of presentations at key conferences in endocrinology

ea0094s4.3 | Hacking the reproductive clock | SFEBES2023

The genetics of the ageing ovary

Stankovic Stasa , Perry John , Murray Anna , Shekari Saleh , Hoffmann Eva , Qin Huang Qin , Martin Hilary , Hurles Matthew

Menopause timing is highly variable, having a direct effect on reproductive lifespan, fertility and health outcomes in later life. Endocrine and imaging tests only record changes in ovarian function that have already taken place, thus disabling early prediction and identification of women with reduced reproductive lifespan. Human genetic studies have attempted to overcome this problem by identifying genetic markers associated with menopause timing and fertility. Using data fro...